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Kind of stupid, isn't it? I think that this demonstrates a phenomenon that extends well beyond attractive girls being treated differently. Societal aesthetics (or attractiveness, if you prefer) in general dictate how you will generally be treated from the socially informal to formal situations.
Many people are unaware of this, and when confronted with the idea, will likely suggest that it has little, if any, significant impact. However, not only have all kinds of studies been performed on how people are treated based on their "aesthetic category," but anecdotal experience confirms this phenomenon.
Even the most seemingly benign manifestations of it, such as how strangers in informal situations speak to you, has an aggregate effect of lowering the person's self-esteem as a result of being talked to like you're less of a person. Then you have more serious effects, like social groups either partially or completely ostracizing and being more likely to be hired and get paid more in a job.
Normally I wouldn't reference a TV show, especially not Family Guy, but there was one episode that touches on this, albeit not for the purpose of social awareness. There is an episode where Peter gets all kinds of cosmetic surgery to make himself look better and, as a result, gets accepted into the "beautiful people's club." He gets educated by a "beautiful mentor" on how he can use it to his advantage: cutting in line, getting free service, treating non-beautiful people like crap, and taking pills (as part of a gift basket to him) to make his poo smell like fresh baked bread. While this is an exaggeration, it does illustrate the concept quite well.
It's mostly a subconscious phenomenon, making it quite insidious and hard for people to acknowledge. The only way to counter it is conscious awareness of how this phenomenon manifests and how to deal with it, including how to call others out on it, to the extent feasible (e.g. on the job it may be risky to your career).